With that list of best seilling games one also has to remember when some of these games were released.
But sims.. really? No wonder they keep making them then, that always puzzled me 
And I cannot believe you put Vanguard on your list. At least when I played it, as it was just released it was bugged insanely. Not even beta worthy. A bard running 3 times faster than a mounted charachter as soon as it picked up drums and off-handers displaying 7 digit crit numbers.. shudders... the map looked awesome though, I just couldnt get over all the bugs to warrant further play.
FAvourite games rated in each category from top down. first being best etc. :
Oldies:
Masters of Orion 2
Warcraft 2
UFO Enemy Unknown
Baldurst Gate 1-2/Icewind Dale 1-2/Planescape: Torment
Magic the Gathering : Shandalar
less Oldies:
Deus Ex - in my opinion, one of the best PC games of all times. Everything was friggin perfect. Music, voice acting, graphics (for its time), story, gameplay.. all of it simply brilliant.
Morrowind - the amount of time sunk into this game...
Monkey Island 3 
Gothic 1 through 3 - number 4 is a disgrace 
OpenTTD
New(er) titles:
Skyrim and oblivion
Sins of a Solar Empire
Galactic Civilizations 2
Civ V (I loved all from 2 to 5)
Mass Effect 1 (and a little 2)
MMOs:
EvE Online - My favourite MMO hands down. By far the best one out there now (and the hardest probably) and as soon as I set food on Danish soil subs will be reopened.
SWG - So I met some guys back in the days in EvE from fountain alliance and we started hanging out on their TS right.. one day, one of them says that hes into SWG.. and I am like.. alright good on you mate, so long as its conscentual. Later turned into be a MMO and it hooked me, it hooked me unlike anything ever did. Slept when servers hit maitanence at 5 am, got up again at 11 am resumed where I left off... half a year later I came to realize where I was headed. Quite scary.
Guild Wars - Also introduced through EvE and though quite adicting too with GvG and all.
Dark Ages of Camelot : They just dont make the third person fantasy mmo's like this anymore 
WoW from Lich King and onward was pants, but I loved Burning Crusade, brilliant 
Others.. serriously awesome games are too many to list.
Colonization? Nobody mentioned this?
Dungeon Keeper
Quake 1-3
Duke Nukem 3D - thumbs up for pixelated boobs.
Armada2526