Hi, I've been a fan of SC2 since the 3DO. I every time I rented the machine I also took this game. I made my mother pay close to a 100$ for SC3. I did not know what currency exchange rate was at the time.
Anyways, I really like the SC multivers idea. You can make a reboot while acknowledging past titles. And you can add new stories and licences. It make me think of Telltale Games. They do exactly that, they tell stories from different licences in a interactive first/third person format. And since most sci-fi univers or stories are centered around Earth, the potential is awesome. You do realize that you've set a high bar? I will be expecting great things in the future.
Here's a small list of univers I would like you to licences. I won't mention the ones that have already been named.
1) Orson Scott Card's, Ender's Game: Epics stories, major space battles but has never seen the beauty of the interactive story telling that a computer game can offer.
2) John Scalzi's, Old Man's War. Excellent book series, lots of aliens to deal with. Best part, there's no good guys. Just people (including aliens) trying to survive.
3) Cowboy Bebop: Every body likes to play mercenary from time to time.
4) Ian M. Banks' Culture book series. I haven't read the whole thing yet but I think there's potential.
5) Farscape: Farscape, Farscape, Farscape...what a TV series. Aliens, living ships, multiple univers', it was made for this.
6) Firefly: One of the best TV series ever made. This story would be limited to a single system and no aliens. But the single system is very big and full of places to visit.
7) Stelaris: I see a lot of potential here for storytelling. You just have to convince Paradox.
On a special note. Before someone says "Minecraft", plz be advise that cubic ships have already been licences by the Borg. As per section A-467 of the Multivers Intellectual Property Rights agreement: No exact copy of one univers' space traveling ship shall be copied and/or reproduced for any reason in an other univers.