Madness... yes, lol. Don't you get lost sometimes when you don't name your layers?
Heh... once in a while, i may name, or group some layers, I think maybe i did a couple on this project, but, for the most part, I find naming, grouping, takes more time than I spend finding the layers by memory.... I'm not naming 250+ layers 
so, to that end, that's my illogical logic (See Fuzzeh)
Here's my method... and.. this may or may not help folks..
1. If i want to access a layer.. I..... click on it ! 
, yes, I know its profound, but that's my science.
2. If a layer I want, is under another layer.. I just click on the upper layer, then travel down thru the layers palette until I find it.
3. I typically.. just remember, after working on something, where layers are, in the layers palette. sort of memorization thru attrition.
4. Photoshop does not install this at default but ALWAYS ALWAYS make sure that when u have the move tool (black arrow) selected, that in the options bar above you have 'Show bounding box" \ "show transform controls" checked (depending on ur PS version) Secondly make sure you have " Auto select" checked as well.
without these being checked... I'd be lost too.
Just a couple of tips from an old and weary skinner.
Off to bed... thanks folks. 
