Actually, CFCs are no longer legal in the US. We are by far not the biggest producer of them anymore, but they spring up due to using older equipment, such as classic cars and outdated machinery. And the hole does not appear where they are used. The ozone layer is made of gas (trioxygen) and moves about as any gas would, evening over an area. Antarctica produces no CFCs due to the lack of human population. So why does it get the hole? The extremely cold winters there cause a whirlpool effect going north, keeping the southern pole from receiving any major circulation. Nitric acid builds up in the clouds, a natural process. Sadly, this process bonds amazingly well with CFCs. When the weather warms up, the sun breaks down a large dose of CFCs and they have their effect, breaking down the trioxygen. In lower atmospheres, this effect would only last the year, but in the stratosphere, it takes about five years to mix things up again. But between the seasonal isolation and continued bath of CFCs, Antarctica gets screwed.
Ta da!