It really depends. You can "generally" safely run 2-3 additional factions from Sins of the Fallen, Transhumans and Blood and Chrome on recommended settings (High/Medium/Low).

However, depending on your system specifications, map size, etc adding more than 3 additional factions may stress the game above 2GB.

That said they are compatible with the latest version of Trinity and can work together.

I'm working on a way to tune the framework to ignore Tech, Advent and Vasari meshes and textures when those factions aren't loaded which should hopefully allow the mod to run on all highest settings when your are running only Colonials and Cylons for example.

@sigie85 - answered your question on moddb 

Here is a design mockup for the new Capital, Fleet and Faction/Trait research screen.

Defense Tree Design/Layout

CIC:

Diplomacy Tree Layout/Design

Quorum of Twelve:

I posted a rough table a few pages back that sucked to read

I'll post some pics like the trees above that are easy to view when I finish up some more of the descriptions and account for some of the changes.

Just thought you guys might like seeing progress while it's happening   

Thanks... I'm trying to add as much Colonial flavor as you can fit reasonably. 

I've made the religion tree fairly large to reflect their monotheistic beliefs.

The Colonization and Trade Unions tree are mostly standard fair right now as a base. I'll probably add a few other options that can be used for the colonials but I don't want it to overshadow their culture benefits.

The Combat and Defense trees are pretty much set for the most part.

I will also add or categorize some of the TECs as Loyalists or Rebels in some later revisions.

Rebel

Declares your faction loyal to the government of the twelve colonies as represented by it's President and represented by it's peoples. 

Trait: Hardliner

You believe all Cylons are Toasters and can't be trusted. You also have a anti-Xeno bigotry that extends to all non-human factions. Your Titan is heavily offensive and capable of inflicting mass damage. 

Trait Bonuses:

All pacts unlocked

ArmorBaseAdjustment

BombingCooldownDecrease

BombingPopulationKilledAsDamageDealerAdjustment

BombingRangeAdjustment

CreditCostAdjustment: Increases Cost

ResourceCostAdjustment: Increases Resource Cost

CultureResistPercent

Trait: Militant

A successful Military coup has resulted in the overthrow of the Colonial President placing control in your hands.

Trait Bonuses:

CapitalShipMaxSlots

CapitalShipWeaponTargetPerBankAdjustment

ExperienceAwardedAdjustment

ExperienceConstantGainRate

ExperienceConstantGainLevelCap

WeaponDamageAdjustment

WeaponRateOfFireAdjustment

Trait: Criminal

You are Tauron born and part of a powerful criminal organization operating with control of Colonial assets.

Trait Bonuses:

BlackMarketBuyPriceAdjustment

BountyCollectedAdjustment

CreditsGainedPerPointOfBombingDamageDealt

IncomePercLost: Helps increase tax income received

PlanetSlotsTacticalIncrease

ResearchCostAdjustment

SalvageWreckagePercent

Trait: Syndicate

Your criminal empire has slowly become an organized crime syndicate further increasing your power.

Trait Bonses:

DerivativeCreditsFromPurchasesPercent

DerivativeCreditsFromTradePercent

SalvageWreckagePercent

ShipBuildRateAdjustment

ShipBuildRateAdjustmentWhenEnemyInGravityWell

StarBaseBuildRateAtEnemyOrbitBodyAdjustment

WeaponDamageAdjustmentWhenInGravityWellBeingBombed

dood! nice. colonials are Polytheistic, the cylons are monotheistic.  you said in one earlier the colonial religious was monotheistic.

Lol, I'm being hounded by the word police

Anyways, this is rough design, not polish text in game. It's more about the essence and layout right now than the verbiage. When it's an actual in game text feel free to correct or provide your own descriptions (I love the latter when people send in better descriptions).

And Ragnarok is a capital ship class in my fallen mod, so I tend to write that sometimes.

So onto the real comments

Due to research constraints I've opted for 4 paths only. You'll start as a Marketeer and then become a Megacorp. Or you can start as a Diplomat and goto Alliance.

So basically 2 sub-paths per faction type with 2 additional researches each.

Yep, I wanted the Colonials to have a lot of religious flavor in their research. Their beliefs are one of the areas that make the Colonials interesting.

There are Tactical Nuclear Weapons and Nuclear Bombardment Research. All the capital class battlestars also have special nuclear class abilities.

harpo

Looking Great Z! you the man!