Desura is still beta. Supposed to be like Impulse or Steam except different. Tied strongly to ModDB.
Looks suspicious to me.
"Wired has a lengthy investigation into the  state of PC game mods, and the amateurs keeping the scene exciting  in the wake of draconian DRM placed on many PC titles by major studios.  It highlights a number of creative modders, such as Scott Reismanis,  founder and editor of Mod DB, and his community-driven alternative to  Valve's Steam — Desura — which is 'a distribution system, and, like Steam, will sell games and  champion indie titles. But the way it handles mods makes it even more  exciting.'" -- Slashdot